We study the structure and mechanism of membrane proteins mediating active transport and protein glycosylation.

• Active transport processes are essential for cellular homeostasis and have a key role in human physiology. We investigate transporters of lipidic substrates including drugs, lipids, and bile salts.
• Glycosylation is the most abundant post-​translational protein modification, and the glycans and carbohydrates attached to proteins are involved in many processes associated with human health and disease. We study glycosyltransferases involved in N-​linked and C-​linked protein glycosylation.

Our goal is to elucidate the mechanistic basis of physiologically important processes and to provide opportunities for drug discovery and bio-​engineering.